Adaptive immunity could colostrum be the key to create a balance?


Put simply, the immune system is a complex network of cells and processes within the body that defends against foreign invaders that shouldn’t be there, such as viruses, bacteria and parasites.  When functioning properly and effectively, the immune system identifies and attacks these threats, whilst distinguishing them from the body’s own healthy tissue.

The immune system can be broadly split into two categories; innate immunity and adaptive immunity. Innate immunity is what you are born with and mainly consists of barriers that keep foreign threats out – it is non-specific – and adaptive immunity is acquired immunity which is more complex than innate immunity. Adaptive immunity targets specific threats and creates antibodies to fight them once the body has processed and recognised them. Adaptive immunity then remembers this threat for possible future invasions.

Adaptive immunity is dependent on the specialised white blood cells known as lymphocytes, which are the cells responsible for the ability to distinguish and react to an almost infinite number of different foreign substances.

Lymphocytes are mainly dormant in the body until they receive the appropriate signals for action.  At any one time, an adult human has 2 x 1012 (that’s 2 trillion!) lymphocytes.  About 1% of this is in the bloodstream with the rest being concentrated in various tissues around the body, mainly in the lymphatic system. Part of the lymphatic system also lies in the lining of the intestines.


It is important to know the difference between boosting your immune system (and bringing it into balance) and an overactive immune system.  Obviously, an underactive immune system is not a good thing as it may not be effective in combatting harmful attacks.  At the other end though, an overactive immune response can also be harmful and lead to issues such as inflammation and autoimmune conditions.  Therefore, it is more important to think about keeping the immune system in balance.

As part of the adaptive immune system (the ‘attack’ team) is located in the gut lining, one way we could help our immune systems is by targeting the gut with what we eat and helping to keep it healthy so that the lining is free from any irritations, inflammations or leakiness. This will help it to function effectively and maintain the population of lymphocytes which are found in the gut.

It is a well-known fact that colostrum plays a vital role in the nourishment and protection of a new-born baby.  This is because colostrum is a complex, nutrient rich biological fluid which is loaded with immune, growth and tissue repair factors, and helps in the development of immunity.  It contains a significant quantity of complement components which act as natural anti-microbial agents that actively stimulate the maturation of a baby’s immune system. 1

Although the benefits of colostrum are so widely known, colostrum from a human mother is not readily available. So, many studies have been conducted on bovine (cow) colostrum.

Bovine colostrum is a rich source of immunoglobulins, a class of proteins present in the serum and the cells of the immune system, which function as antibodies. It’s been shown to be actively functional through the digestive tract in humans and a large number of studies have shown that bovine colostrum can prevent gastrointestinal tract infections and upper respiratory tract infections.2,3 Bovine milk and its components have clear functional effects on the human immune system and bovine immunoglobulin can bind to a wide range of pathogenic bacteria and viruses, as well as to many allergens.4


Toxaprevent Medi ACUTE Capsules contain the active ingredient MANC® (Modified and Activated Natural Clinoptilolite) which is a clean form of clinoptilolite zeolite and is patented for its ability to bind to and remove heavy metals, histamine and ammonium from the body. Studies have shown that MANC® strengthens the intestinal barrier and reduces intestinal permeability by binding to and removing inflammatory mediators including histamine.  Since part of the lymphatic system which is responsible for adaptive immunity is found in the intestinal lining, keeping the lining strong and irritation free would benefit hugely in the effectiveness of adaptive immunity.

The ACUTE Capsules have the benefit of the addition of high-quality colostrum (bovine, decaseinated) which will help with the strengthening of the immune system and bringing it back into balance.  Studies have shown that bovine colostrum has a number of similar effects in humans as breast milk, such as strengthening the immune function and help with protecting against gastrointestinal tract and respiratory tract infections.


  1. Colostrum and its benefits: a review (F.O Uruakpa, M.A.H Ismond, E.N.T Akobundu)
  2. Effects of Bovine Immunoglobulins on Immune Function, Allergy and Infection (Laurien H. Ulfman, Jeanette H. W. Leusen, Huub F. J. Savelkoul, John O. Warner and R. J. Joost van Neerven)
  3. Effects of bovine colostrum on recurrent respiratory tract infections and diarrhea in children Khaled Saad, MD,a,Mohamed Gamil M. Abo-Elela, MD,b Khaled A. Abd El-Baseer, MD,b Ahmed E. Ahmed, MD,b Faisal-Alkhateeb Ahmad, MD,a Mostafa S. K. Tawfeek, MD,a Amira A. El-Houfey, PhD,c Mohamed Diab Aboul_Khair, MD,d Ahmad M. Abdel-Salam, MPharm,e Amir Abo-elgheit, MD,a Heba Qubaisy, MD,b Ahmed M. Ali, MD,a and Eman Abdel-Mawgoud, MDb
  4. Kelly GS. Bovine colostrums: a review of clinical uses. Altern Med Rev.(2003) 8:378–94. [PubMed] [Google Scholar]
  5. Rump JA, Arndt R, Arnold A, Bendick C, Dichtelmuller H, Franke M, et al. . Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clin Investig. (1992) 70:588–94. [PubMed] [Google Scholar]
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